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Breast & Ovarian Cancer

Information on genes associated with Hereditary Breast and Ovarian Cancer

DIPLOIDE is dedicated to utilizing genomics in order to advance precision medicine for cancer. DIPLOIDE’s next-generation sequencing assays offer a variety of options, including targeted panels that analyze genes directly linked to specific cancers by well documented scientific research, and also much larger cancer panels designed for cancer analysis and discovery.

DIPLOIDE’s cancer panels are designed to identify all four classes of actionable genomic alterations, including base substitutions, insertions and deletions, copy number alterations and selected fusions. Both tissue samples and liquid biopsy samples are supported (except for the Sentis Colorectal Cancer Panel for which a liquid biopsy version is still being developed).

DIPLOIDE’s Hereditary Breast and Ovarian (HBOC) panel provides health providers  with information on 21 genes associated with Hereditary Breast and Ovarian Cancer (HBOC) based on recent scientific and clinical literature. DIPLOIDE detects different alterations including germline SNV, Indels and CNVs.

  • Comprehensive: complete exome plus covered flanking intronic regions for all genes tested; A single assay that detects point mutations, deletions, insertions, duplications, rearrangements.

  • Robust: Clinically important variants (pathogenic or likely pathogenic) are verified by Sanger sequencing, while qPCR verifies large genetic rearrangements.

  • Convenient: blood or saliva tests; DNA is also accepted.

  • Professional: the latest generation variant database guarantees up-to-date analysis and interpretation.

How it works
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